Received 09.01.2023
DOI: 10.35556/idr-2023-2(103)52-57

Prevalence of COVID-19 manifestations in the oral cavity among persons aged 18 to 30 years
Tokmakova S.I.1, ORCID ID: 0000-0003-0437-0079, Bondarenko O.V.1, ORCID ID: 0000-0001-7280-7709, Lunitsina Yu.V.1, ORCID ID: 0000-0002-2442-3361, Chudova L.V.1, ORCID ID: 0000-0001-5002-9352, Zyablitskaya K.V.1, ORCID ID: 0000-0002-6451-9421, Gurevich Yu.Yu.1, ORCID ID: 0000-0003-1280-0702, Mokrenko E.V.2, ORCID ID: 0000-0002-4286-3993, Gaidarova T.A.2, ORCID ID: 0000-0002-6415-0767
1 Federal State Budgetary Educational Institution of Higher Education “Altay State Medical University” of the Ministry of Healthcare of the Russian Federation
Russia, 656038, Barnaul, Leninа Ave., 40
2 Federal State Budgetary Educational Institution of Higher Education “Irkutsk State Medical University” of the Ministry of Healthcare of the Russian Federation
Russia, 664003, Irkutsk, Krasnoarmeyskaya St., 1

E-mail address:

The article presents the results of a survey of young people from 18 to 30 years who have undergone COVID-19. The study conducted a quantitative and qualitative analysis of lesions of the oral mucosa in medical university students during the period of COVID-19 disease and after recovery and identified the most common lesions of the oral mucosa associated with coronavirus infection. Pathological changes in the oral cavity have been identified, including with a mild course of coronavirus infection, reducing the quality of life, health and without timely treatment, leading to serious consequences. The obtained results of the study and the high percentage of manifestations characterizing postcovid syndrome justify the need for dental examination of these patients after their clinical recovery. The relationship between the course of the underlying disease COVID-19 and the severity of the lesion of the oral mucosa was revealed. It is determined that the more complex the form of the underlying disease, the longer and more severe the duration of dental symptoms. The role of a dentist in the timely diagnosis of dental manifestations in patients who have had a coronavirus infection and the selection of the most adapted treatment regimen depending on the clinical manifestations in the oral cavity in order to prevent the development of complications and the severe course of the identified pathology is shown.

Keywords: COVID-19, postcovid syndrome, oral mucous membrane, oral cavity, manifestations of COVID-19.

For citation: Tokmakova S.I., Bondarenko O.V., Lunitsina Yu.V., Chudova L.V., Zyablitskaya K.V., Gurevich Yu.Yu., Mokrenko E.V., Gaidarova T.A. Prevalence of COVID-19 manifestations in the oral cavity among persons from 18 to 30 years. Stomatology for All / Int. Dental Review. 2023, no.2(103): 52-57 (In Russian). doi: 10.35556/idr-2023-2(103)52-57

1. Brandini D.A., Takamiya A.S., Thakkar P., Schaller S., Rahat R., Naqvi A.R. Covid-19 and oral diseases: Crosstalk, synergy or association? Reviews Medical Virologi. 2021, 31(6): 22—26. doi: 10.1002/rmv.2226
2. Makedonova Yu.A. et al. Manifestation of diseases of the oral mucosa in patients with COVID-19. Bulletin of the Volgograd State Medical University. 2021, no.1(77): 110—115 (In Russian). doi: 10.19163/1994-9480-2021-1(77)-110-115
3. Gherlone E.F., Polizzi E., Tetè G., et al. Frequent and Persistent Salivary Gland Ectasia and Oral Disease After COVID-19. Journal of Dental Research. 2021, 100(5): 464—471. doi: 10.1177/0022034521997112
4 Khabadze Z.S., Sobolev K.E., Todua I.M., Mordanov O.S. Oral mucosal and global changes in COVID 19 (SARS-CoV-2): a single center descriptive study. Endodontics Today. 2020, 18(2): 4—9 (In Russian). doi: 10.36377/1683-2981-2020-18-2-4-9
5. Klein H., Asseo K., Karni N., Benjamini Y., Nir-Paz R., Muszkat M., Israel S., Niv M.Y. Onset, duration and unresolved symptoms, including smell and taste changes, in mild COVID-19 infection: a cohort study in Israeli patients. ClinMicrobiol Infect. 2021, 27(5): 769—774. doi: 10.1016/j.cmi.2021.02.008
6. Vaira L.A., Salzano G., Fois A.G., Piombino P., De Riu G. Potential pathogenesis of ageusia and anosmia in COVID-19 patients. International Forum Allergy Rhinology. 2020, 10(9): 1103—1104. doi: 10.1002/alr.22593
7. Sakalli E., Temirbekov D., Bayri E., Alis E.E., Erdurak S.C., Bayraktaroglu M. Ear nose throat-related symptoms with a focus on loss of smell and/or taste in COVID-19 patients. Am J Otolaryngol. 2020, 41(6): 102622. doi: 10.1016/j.amjoto.2020.102622
8. Voitenkov V.B., Ekusheva E.V., Bedova M.A. Anosmia and ageusia in patients with COVID-19 infection. Folia Otorhinolaryngologiae et Pathologiae Respiratoriae. 2020, 26(3): 23—28 (In Russian). doi: 10.33848/foliorl23103825-2020-26-3-23-28
9. Glushchenko E.I., Symon A.M. The most likely causes of impaired smell and taste perception in COVID-19. University medicine of the Urals. 2020, no.7(24): 16—17 (In Russian). eLIBRARY ID: 45682996
10. Bigday E.V., Samoilov V.O. Olfactory dysfunction as an indicator of the early stage of COVID-19 disease. Integrative Physiology. 2020, no.1(3): 187—195 (In Russian). doi: 10.33910/2687-1270-2020-1-3-187-195
11. Hupsch-Marzec H., Dziedzic A., Skaba D., Tanasiewicz M. The spectrum of non-characteristic oral manifestations in COVID-19 — a scoping brief commentary. Medycyna Pracy. 2021, 72(6): 685—692. doi: 10.13075/mp.5893.01135
12. Egido-Moreno S., Valls-Roca-Umbert J., Jane-Salas E., Lopez-Lopez J., Estrugo-Devesa A. COVID19 and oral lesions, short communication and review. Journal of clinical and experimental dentistry. 2021, 13(3): 8. doi: 10.4317/jced.57981
13. Martin Carreras-Presas C., Amaro Sanchez J., Lopez-Sanchez A. F., Jane-Salas E., Somacarrera Pérez M.L. Oral vesiculobullous lesions associated with SARS-CoV-2 infection. Oral diseases. 2021, 27(3): 710—712. doi: 10.1111/odi.13382
14. Rusu L.C., Ardelean L.C., Tigmeanu C.V., Matichescu A., Sauciur I., Bratu E.A. COVID-19 and Its Repercussions on Oral Health: A Review. Medicina (Kaunas). 2021, 57(11): 11—89. doi: 10.3390/medicina57111189
15. Sinadinos A., Shelswell J. Oral ulceration and blistering in patients with COVID-19. Evidence Based Dentistry. 2020, 21(2): 49. doi: 10.1038/s41432-020-0100-z
16. Sulaymonova G.T., Shomuratova R.K., Akhmedova F.N. Characteristics of changes in the mucous membrane and microflora of the oral cavity during coronovirus infection. Science and education: problems and innovations. 2021: 153—159 (In Russian). eLIBRARY ID: 45682996
17. Toporkov A.V., Lipnitsky A.V., Polovets N.V., Viktorov D.V., Surkova R.S. Invasive mycoses-coinfections COVID-19. Article in the open archive. 2021, no.3111961: 4—6. (In Russian).
18. Nuno Gonzalez A., Magaletskyy K., Martin Carrillo P., Lozano Masdemont B., Mayor Ibarguren A., Feito Rodriguez M., Herranz Pinto P. Are Oral Mucosal Changes a Sign of COVID-19? A Cross-Sectional Study at a Field Hospital. Actas Dermosifiliogr (Engl Ed). 2021, 112(7): 640—644. doi: 10.1016/
19. Surboyo M.D., Ernawati D.S., Budi H.S. Oral mucosal lesions and oral symptoms of the SARS-CoV-2 infection. Minerva Dent Oral Sci. 2021, 70(4): 161—168. doi: 10.23736/S2724-6329.21.04493-9