Received 13.01.2022
DOI: 10.35556/idr-2022-2(99)46-53
The influence of the composition of the gel Soderm®-Forte and the metabolic energy corrector cytoflavin on the course of the inflammatory process in the conditions of experimental periodontitis
Popkov V.L.1, Zadorozhny М.A.2, Heigetyan A.V.2, Galenko-Yarochevsky P.A.1
¹ Federal State Budgetary Educational Institution of Higher Education “Kuban State Medical University” of the Ministry of Healthcare of the Russian Federation
Russia, 350063, Krasnodar, St. Mitrofana Sedina, 4
² Federal State Budgetary Educational Institution of Higher Education “Rostov State Medical University” of the Ministry of Healthcare of the Russian Federation
Russia, 344022, Rostov-on-Don, Per. Nakhichevanskiy, 29

Е-mail address: vict.popkoff2015@yandex.ru
Summary
The study explored the possibility of combining the multitargent means of gel Soderm®-Forte and the metabolic energy corrector Cytoflavin in conditions of inflammatory pathology of periodontal tissues on a model of induced experimental periodontitis in rats. It is shown that the conduct of complex pharmacotherapy with drugs with antimicrobial, anti-inflammatory, energy-correcting and antioxidant orientation helps to reduce inflammatory phenomena in periodontal tissues, normalize osmotic exudation of the gingival fluid of the sulcular region and restore the index assessment of the tissues of the periodontal complex.
The paper substantiates and shows the significance of the use of these drugs that can have a prolonged therapeutic effect on the peripheral microvascular network in the region of the gingival groove, reducing the exudative component in the postcapillary venules and arterioles by lowering perfusion pressure and reducing their permeability and improving protective effects under hypoxia.

Keywords: model of experimental periodontitis, gel Soderm®-Forte, Cytoflavin, gingival fluid.

For citation: Popkov V.L., Zadorozhny М.A., Heigetyan A.V., Galenko-Yarochevsky P.A. The influence of the composition of the gel Soderm®-Forte and the metabolic energy corrector cytoflavin on the course of the inflammatory process in the conditions of experimental periodontitis. Stomatology for All / Int. Dental Review. 2022, no.2(99): 46-53 (In Russian). doi: 10.35556/idr-2022-2(99)46-53

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