Received 01/06/2024
DOI: 10.35556/idr-2024-3(108)10-17
A prospective analysis of the distribution of diseases of the oral mucosa in the “pre-covid” and COVID-19 periods
Kamishnikova I.O., ORCID ID: 0000-0002-0665-043X;
Zaporozhskaya-Abramova E.S., ORCID ID: 0000-0003-0675-6581;
Adamchik A.A., ORCID ID: 0000-0002-2861-0260;
Dorogan V.V., ORCID ID: 0000-0002-4799-866X;
Tairov V.V., ORCID ID: 0000-0003-0379-5964;
Risovannaya O.N., ORCID ID: 0000-0001-9585-4444
Federal State Budgetary Educational Institution of Higher Education “Kuban State Medical University” of the Ministry of Health of the Russian Federation
350063, Russian Federation, Krasnodar, Mitrofan Sedin St., 4
E-mail address: dr.katerina_abramova@mail.ru
Summary
Over the past decades, cases of diseases of the oral mucosa (MSM) and the red border of the lips (RLB) have become significantly more frequent, and the severity of the course of diseases has increased markedly. Some diseases of SOP are prone to relapses, their treatment is not always successful. These diseases often lead to serious complications, including malignant ones. The outbreak of COVID-19 coronavirus infection was also one of the reasons that influenced the increase in the volume and variety of manifestations of MSM diseases.
The purpose. To study the structure of MSM diseases in the “pre-epidemic” period and against the background of the pandemic of the new coronavirus infection COVID-19.
Material and methods. The research was conducted on the basis of the therapeutic and prophylactic department of the clinic of the Federal State Budgetary Institution of the Ministry of Health of the Russian Federation. As part of the consultation, 988 patients with various diseases of MSM were examined from 2018 to 2022. The most common nosological forms of MSM diseases were identified. The patients were divided into 2 groups: group 1 – patients examined during the “pre-covid” period and group 2 – patients examined during the COVID-19 pandemic. All patients underwent the generally accepted methods of examination in the clinic (collection of complaints, anamnesis, examination of the litter, palpation). According to the indications, the presence of galvanism phenomena in the mouth (in the presence of orthopedic structures) was determined, bacterioscopic examination was performed and, in some cases, mainly for differential diagnosis, cytological examination and examination of the mucous membrane in the rays of a Wood lamp.
Results and discussion. Analyzing the data obtained, we concluded that the overall increase in the number of patients who applied for MSM diseases in 2020-2022 increased the number of young patients aged 20 to 35 years. In the structure of diseases, the number of patients with such diseases as lichen planus (RLP), desquamative glossitis and glossalgia has increased. In the structure of dental lesions, cases of combined pathology of MSM diseases have become more frequent.
Conclusions. In the complex of diagnostic studies of patients with MSM disease on the background of a coronavirus infection, in addition to a standard examination, it is necessary to introduce a general clinical examination by specialists such as a gastroenterologist, immunologist, neurologist, psychotherapist, dermatologist and others. Based on the etiology and clinic of MSM diseases in this category of patients, in addition to the prescribed generally accepted treatment regimens, it is necessary to prescribe drugs with effects on the autonomic and central nervous systems, as well as drugs that restore the intestinal and oral microflora.
Keywords: new coronavirus infection, COVID-19, diseases of the oral mucosa.
For citation: Kamishnikova I.O., Zaporozhskaya-Abramova E.S., Adamchik A.A., Dorogan V.V., Tairov V.V., Risovannaya O.N. A prospective analysis of the distribution of dis-eases of the oral mucosa in the “pre-covid” and COVID-19 periods. Stomatology for All / Int. Dental Review. 2024; no.3(108): 10-17 (in Russian). doi: 10.35556/idr-2024-3(108)10-17
References
1. Serikova O.V., Shumilovich B.R., Filippova Z.A., Shcherbachenko O.I. Dynamics of the clinical picture in the treatment of patients with severe forms of lichen planus of the oral mucosa and red lip border using physical methods. Periodontics. 2021; 26(1): 44–51 (in Russian). doi: 10.33925/1683-3759-2021-26-1-44-51
2. Shkarin V.V., Makedonova Yu.A., Dyachenko S.V. Development of a routing scheme for patients with diseases of the oral mucosa. Medical and pharmaceutical magazine “Pulse”. 2022; 24, no. 4: 131-137 (in Russian). doi: 10.26787/nydha-2686-6838-2022-24-4-131-137
3. Blashkova S.L., Fazylova Yu.V., Ushakova M.A. Modern aspects of local pathogenetic therapy of chronic recurrent stomatitis. Periodontics. 2018; 24(4): 77–80 (in Russian). doi: 10.25636/PMP.1.2018.4.14
4. Makedonova Yu.A., Poroyskiy S.V., Gavrikova L.M., Afanasyeva O.Yu., Dyachenko S.V., Alexandrina E.S. Comparative analysis of the effectiveness of treatment of traumatic lesions of the oral mucosa in patients with concomitant pathology. Periodontics. 2021; 26(3): 229–233 (in Russian). doi: 10.33925/1683-3759-2021-26-3-229-233
5. Bakaev Zh.N., Yunusova U.A. The relationship of somatic pathology with diseases of the oral mucosa (Literature review). Central Asian Journal of Medical and Natural Science. 2022; 3(5): 317–324 (in Russian). doi: 10.17605/cajmns.v3i5.1098
6. Orekhova L.Yu., Osipova M.V., Ladyko A.A. The model of development, prevention and treatment of lichen planus of the oral mucosa. Part II. Periodontics. 2019; 24(1): 57–62 (in Russian). doi: 10.25636/PMP.1.2019.1.10
7. Uspenskaya O.A., Shevchenko E.A., Kazarina N.V., Legostaeva M.V. The state of oral microbiocenosis in desquamative glossitis associated with the syndrome of excessive bacterial growth in the small intestine. Periodontics. 2019: 24(1): 39–43 (in Russian). doi: 10.25636/PMP.1.2019.1.7
8. Usmanova I.N., Galimova I.A., Khusnarizanova R.F., Ishmukhametova A.N., Lakman I.A., Al Mohamed M.A. Features of the composition of the microbiota of the oral cavity against the background of classical and mediated acid-dependent diseases of the gastrointestinal tract. Periodontics. 2022; 27(1): 91–99 (in Russian). doi: 10.33925/1683-3759-2022-27-1-91-99
9. Chudova L.V., Tokmakova S.I., Lunitsyna Yu.V., Zyablitskaya K.V., Richter A.A., Nikulina V.D. Causes and clinical manifestations of lesions of the oral mucosa that occur against the background of COVID-19. Periodontics. 2022; 27(2): 183–192 (in Russian). doi: 10.33925/1683-3759-2022-27-2-183-192
10. Chan J.-W., Yuan S., Kok K.-H., To K.-W., Chu H., Yang J., et al. A familial cluster of pneumonia associated with the 2019 novel coronavirus indicating person-to-person transmission: A study of a family cluster. The Lancet. 2020; 395(10223): 514–523. doi: 10.1016/S0140-6736(20)30154-9
11. Belotserkovskaya Yu.G., Romanovskikh A.G., Smirnov I.P. COVID-19: Respiratory infection caused by a new coronavirus: new data on epidemiology, clinical course, patient management. Consilium Medicum. 2020; no. 3. doi: 10.26442/20751753.2020.3.200092
12. McLachlan C.S. The angiotensin-converting enzyme 2 (ACE2) receptor in the prevention and treatment of COVID-19 are distinctly different paradigms. Clin Hypertens. 2020; 26, 14. doi: 10.1186/s40885-020-00147-x
13. Carreras-Presas C.M., Sanchez J.A., Lopez-Sanchez A.F., Jane-Salas E., Somacarrera Perez M.L. Oral vesiculobullous lesions associated with SARS-CoV-2 infection. Oral Diseases. 2020; 27(S3): 710–712. doi: 10.1111/odi.13382
14. Najm Al-Magsoosi M.J., Baqer Al-Asadi O.K., Al-Quraine N.T., Sami S.M., Haider J. Oral Manifestations Associated with COVID-19 Infection: A Cross-Sectional Study of Recovered Iraqi Patients. International Journal of Dentistry. 2023; no. 1: 4288182. doi: 10.1155/2023/4288182
15. Meircurius D. Surboyo, Diah S. Ernawati, Hendrik S. Budi. Oral mucosal lesions and oral symptoms of the SARS-CoV-2 infection. Minerva Dental and Oral Science. 2021; 70(4): 161–8. doi: 10.23736/S2724-6329.21.04493-9
16. Starikova I.V., Piterskaya N.V., Chaplieva E.M., Bobrov D.S. Psychosomatic aspects of diseases of the oral mucosa. Bulletin of the VolgSMU. 2021; 18, no. 2: 137–140 (in Russian). doi: 10.19163/1994-9480-2021-2(78)-137-140
17. Krikheli N.I., Brusenina N.D., Rybalkina E.A., Bychkova M.N. Systemic correction of psychoemotional disorders in the treatment of dry form of exfoliative cheilitis. Russian stomatology. 2019; no. 12(2): 3–6 (in Russian). doi: 10.17116/rosstat2019120213
18. Isakov V.A., Isakov D.V., Arkhipova E.I., Arkhipov G.S., Nikitina N.N. New coronavirus infection. Bulletin of NovGU. 2020; no. 3(119): 10–15 (in Russian). doi: 10.34680/2076-8052.2020.3(119).10-15
19. Kanorsky S.G. Postcovid syndrome: prevalence and pathogenesis of organ lesions, directions of correction. A systematic review. Kuban Scientific Medical Bulletin. 2021; 28(6): 90-116. doi: 10.25207/1608-6228-2021-28-6-90-11620. Sabino-Silva R., Jardim A.C.G., Siqueira W.L. Coronavirus COVID-19 impacts to dentistry and potential salivary diagnosis. Clinical Oral Investigations. 2020; 24: 1619–1621 (in Russian). doi: 10.1007/s00784-020-03248-x
20. Sabino-Silva R., Jardim A.C.G., Siqueira W.L. Coronavirus COVID-19 impacts to dentistry and potential salivary diagnosis. Clinical Oral Investigations. 2020; 24: 1619–1621. doi: 10.1007/s00784-020-03248-x
21. Vaira L.A., Salzano G., Fois A.G., Piombino P., De Riu G. Potential pathogenesis of ageusia and anosmia in COVID-19 patients. International Forum Allergy Rhinology. 2020; 10(9): 1103–1104. doi: 10.1002/alr.22593
22. Gherlone E.F., Polizzi E., Tete G., et al. Frequent and Persistent Salivary Gland Ectasia and Oral Disease After COVID-19. Journal of Dental Research. 2021; 100(5): 464–471. doi: 10.1177/0022034521997112
23. Sandler I.V., Amkhadova M.A. Pathophysiological and clinical aspects of comorbidity of coronavirus disease and chronic generalized periodontitis (literature review). Stomatology for All / Int. Dental Review. 2023, no. 1(102): 48–55 (in Russian). doi: 10.35556/idr-2023-1(102)48-55