Received 27.06.2025
DOI: 10.35556/idr-2025-3(112)4-7

Characteristics of changes in blood hemostatic parameters and microcirculation disorders in diffuse purulent-inflammatory processes of the maxillofacial region and neck as an early screening of complication
Kravec V.I.1,2, ORCID: 0000-0002-6345-3993
Khelminskaya N.M.1,2, ORCID: 0000-0002-3627-9109
Posadskaya A.V.1,2, ORCID: 0000-0002-5926-8541
Yeremin D.A.1, ORCID: 0000-0003-4077-6359
Techiev S.K.2, ORCID: 0000-0003-1377-0410
Kravec A.V.1, ORCID: 0000-0003-2744-5643
1 Federal State Autonomous Educational Institution of Higher Education «N.I. Pirogov Russian National Research Medical University» of the Ministry of Health of the Russian Federation
117513, Russia, Moscow, Ostrovityanova St., 1
2 N.I. Pirogov Moscow City Clinical Hospital № 1
119049, Russia, Moscow, Leninsky Prospekt, 8

E-mail address: Khelminskaya@mail.ru

Summary
The study analyzes the parameters of laboratory screening of a coagulogram in conditions of a diffuse purulent-inflammatory process of the maxillofacial region and neck in a septic state.
We studied 12 case histories of patients with the diagnosis of “odontogenic phlegmon of the floor of the oral cavity who were undergoing inpatient treatment at the Department of Maxillofacial Surgery of the N.I. Pyrogov State Clinical Hospital No. 1 in Moscow.
The traditional coagulation parameters were studied – prothrombin time (PV), international normalized ratio (INR), activated partial thromboplastin time (APTT) and fibrinogen concentration, as well as additional indicators D-dimer and Antithrombin III.
It is concluded that the diagnostic study of D-dimer and Antithrombin III makes it possible to diagnose early disorders in the anticoagulant and fibrinolytic systems of the blood, its procoagulant state.

Keywords: microcirculatory bed, purulent-inflammatory, maxillofacial, blood rheology, D-dimer, Antithrombin III.

For citation: Kravec V.I., Khelminskaya N.M., Posadskaya A.V., Yeremin D.A., Techiev S.K., Kravec A.V. Characteristics of changes in blood hemostatic parameters and microcirculation disorders in diffuse purulent-inflammatory processes of the maxillofacial region and neck as an early screening of complication. Stomatology for All / Int. Dental Review. 2025; no. 3 (112): 4–7 (in Russian). doi: 10.35556/idr-2025-3(112) 4-7

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