DOI: 10.35556/idr-2020-4(93)51-57
Research of matrix metalloproteinases in therapeutic dentistry
Shalamay L.I., Nechai E.Y., Sakerina A.I., Gabdullin A.G.
Federal State Budgetary Educational Institution of Higher
Education “Academician I.P. Pavlov First St. Petersburg State Medical University” of the Ministry of Healthcare of the Russian Federation
197022, Russia, L’vaTolstogo St., 6-8, Saint Petersburg
E-mail address:

This article the properties of matrix metalloproteinases, their classification, function and role in the development of dental diseases are presented. The analysis of matrix metalloproteinases has been performed, which proves their important role in the physiological and pathological processes of the oral cavity. The possibility of using matrix metalloproteinases as part of one of the methods for diagnosing diseases and using them to evaluate the effectiveness of treatment has been considered. The structure of different types of metalloproteinases, as well as a model of the catalytic domain of the MMP-8 molecule has been presented.

Keywords: caries, pulpitis, periodontitis, tissue metalloproteinase inhibitors, extracellular matrix, collagen.

For citation: Shalamay L.I., Nechai E.Yu., Sakerina A.I., Gabdullin A.G. Research of matrix metalloproteinases in therapeutic dentistry. Stomatology for All / Int. Dental Review. 2020, no.4(93): 51-57 (In Russian). doi: 10.35556/idr-2020-4(93)51-57

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