DOI: 10.35556/idr-2020-2(91)12-16
The effect of combining nanosilver and new injection form of rexod on the periodontal tissues state on experimental periodontitis in rats

Leontyev V.K.1, Tseluyko K.V.2, Zadorozhny A.V.2, Popkov V.L.3, Galenko-Yarochevsky P.A.3
1 Federal State Budgetary Educational Institution of Higher Education “A.I. Yevdokimov Moscow State University of Medicine and Dentistry” of the Ministry of Healthcare of the Russian Federation, 127473, Russia, Moscow, Delegatskaya St., 20, bld. 1
2 Rostov State Medical University, 344022, Russia, Rostov-na-Donu, per. Nakhichevanskiy, 29
3 Kuban State Medical University
350063, Russia, Krasnodarskiy kray,Krasnodar, Ulitsa Mitrofana Sedina, 4

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A representative and randomized study of the effect of a combination of nanosilver and a new injection form of Rexod® on the periodontal tissues state of animals (rats) in an experimental model of inflammatory pathology of periodontal tissues (experimental periodontitis) was carried out.
It was shown that the improvement of the dental status of periodontal tissues against the background of the course application of a combination of nanosilver (topically) and a new injection form of Rexod® was accompanied by a decrease in the amount of gingival fluid of the sulcular gingival sulcus, an improvement in the clinical condition of the marginal periodontal mucosa (hyperemia was leveled, swelling decreased, the bleeding indexPBI Muhllemann-Cowell decreased, test Schiller-Pisarev results normalised).
The decrease in the number of gum fluids is due to the decrease in antibacterial activity of pathogenic microflora and their products of their life-based hemodynamics of the peripheral microvascular network (exchange capabulars) of the periodontal, a decrease in perfusion pressure in them, reduced (narrowing) of their lumen, reduce their permeability and restoration of oxidation-reduction processes.

Keywords: experimental periodontitis, nanosilver, gum fluid.

For citation: Leontyev V.K., Tseluyko K.V., Zadorozhny A.V., Popkov V.L., Galenko-Yarochevsky P.A. Influence combinnation of nanosilverand new injectionform rexoda on the state of the partonta experimental periodontitis in rats. Stomatology for All / Int. Dental Review. 2020, no.2(91),12-16 (In Russian). doi: 10.35556/idr-2020-2(91)12-16


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